Collection concerning the Medici family, their numerous enterprises (including banking, manufacturing, and commerce), as well as their political, diplomatic, and governmental positions in Florence, covering the years 1219-1796 (with the bulk of the material from the 16th and 17th century). The documents that compose the collection are divided into four broad sections, one dedicated to papers of individual family members; the second to documents grouped by topic; the third to filze, miscellanies primarily of business and legal documents; and the fourth to oversize items from the other three series. The first one, arranged alphabetically by name, then chronologically for each person, features documents pertaining to about 50 different Medici family members, including the grand-dukes of Tuscany and some of the most prominent Florentine bankers, such as Vincenzo de' Medici. The second one, arranged alphabetically by subject, and chronologically within each subject, is comprised, for the most part, of numerous kinds financial documents (including accounts, receipts, orders, payments, etc.) related to manufacturing, mint operations, and miscellaneous commercial activities; documents pertaining to the operations of the Medici-Capponi bank; and documents related to different aspects of rural life and farm management (such as the purchase of cattle and grains, and the administration of the farms of Trespiano and Bravieri). The third series consists of thirteen disbound miscellanies called filze arranged alphabetically by the letter that appears on the original binding or title page of the filza. Within each filza, the gatherings are arranged in the order in which they were bound. The fourth series comprises larger items pertaining to various members of the Medici family (such as Carlo, Fabrizio, and Vincenzo de' Medici) as well as documents that were previously folded and bound with the filze.