Edward E. and Bertha Giffen graduated from Hastings College, a Presbyterian college in Hastings, Nebraska. Judging from their letters their families resided in Nebraska as well. In 1894, they became missionaries in Hankow, China. In 1895, they transferred to Ching-Ku. In 1896 Bertha contracted tuberculosis, which cut short their mission and forced their return to the United States.
From the guide to the Giffen Family papers, 1894-1896, (Special Collections and University Archives, University of Oregon Libraries)