Alexander Henderson was the first member of the Henderson family to emigrate to the United States, arriving from from Glasgow, Scotland in 1756. He settled in Virginia to serve as the American representative of several Scottish mercantile firms. Alexander's brother, Richard, and his nephew, Alexander, also settled in America and were engaged in mercantile activities. In 1773, Alexander married Sarah Moore of Colchester, Va. The two had six sons, three of whom were sent to Ohio in 1799 to open up the new territory. Their other three sons entered professions. They also had four daughters. One of their sons, Archibald (1783-1859) married Anne Maria Cazenove (1803-1859), daughter of Anthony Charles Cazenove. Archibald and Anne had nine children. One of their daughters, Charlotte Shepard Henderson married Eleuthere Irenee du Pont. The du Ponts' daughter, Marguerite Lammot (1862-1936) married Cazenove Gardner Lee of Alexandria, Va.
Marguerite du Pont Lee preserved the collection of Henderson family papers and passed them on to her daughter-in-law, Dorothy Vandegrit Lee. An inventory was compiled under her direction.
From the description of Inventory of papers, 1771-1867, 1967. (Winterthur Library). WorldCat record id: 122503732