Samuel Patterson was born on March 27, 1800, the son of General Thomas Patterson (1764-1841) and Elizabeth Findley of Cross Creek Township, Pennsylvania. He had ten siblings: William, James, John, Thomas, Findley, Moses, David, Mary, Elizabeth, and Rosanna. Samuel Patterson became a farmer in Cross Creek Township, where he raised sheep for wool. He and his wife, Anne McClave, had ten surviving children: Thomas, Lydia, Eliza, Stewart, Robert M. (b. 1829), Eleanor, Mary A., Harriet, Rosanna, and Adeline. Patterson later moved to Bedford County, Virginia, and his son Robert inherited his Pennsylvania farm. Samuel Patterson died on July 2, 1858.
From the guide to the Samuel Patterson collection, Patterson, Samuel collection, 1831-1865, 1835-1853, (William L. Clements Library, University of Michigan)