In 1809 American Elizabeth Ann Seton, founded the Sisters of Charity of St. Joseph's, adapting the rule of the French Daughters of Charity for her Emmitsburg, Maryland, community.
In 1817, Mother Seton sent three Sisters to New York City to establish an orphanage. In 1829, four Sisters of Charity from Emmitsburg, Maryland, traveled to Cincinnati, to open St. Peter’s Girl’s Orphan Asylum and School. In 1850, the Sulpician priests of Baltimore successfully negotiated that the Emmitsburg community be united with the international community based in Paris. The foundations in New York and Cincinnati decided to become independent diocesan congregations. Six separate religious congregations trace their roots to the beginnings of the Sisters of Charity in Emmitsburg. In addition to the original community of Sisters at Emmitsburg (now part of the Vincentian order), they are based in New York City; Cincinnati, Ohio; Halifax, Nova Scotia; Convent Station, New Jersey; and Greensburg, Pennsylvania.
In 2011, the Daughters of Charity established The Province of St. Louise, bringing together the West Central, East Central, Southeast, and Northeast Provinces of the United States. Los Altos Hills in California remains a separate province.