In 1879 the Kappa Psi Fraternity was founded for medical and pharmacy students. A chapter was established at the University of North Carolina in 1915. In 1925 Kappa Psi officially split into the Kappa Psi Pharmaceutical Fraternity and the Theta Kappa Psi Medical Fraternity. The two orgainizations then issued new charters to the chapters. The Upsilon Chapter of the Theta Kappa Psi Medical Fraternity drew members from the University of North Carolina School of Medicine, while the Beta Xi Chapter of the Kappa Psi Pharmaceutical Fraternity drew members from the School of Pharmacy. The Beta Xi Chapter continues today, but the Upsilon Chapter is no longer active.
From the description of Upsilon Chapter of Theta Kappa Psi Medical Fraternity Records, circa 1926. WorldCat record id: 259459048
From the guide to the Upsilon Chapter of Theta Kappa Psi Medical Fraternity Records, circa 1926, (University of North Carolina at Chapel Hill. Library. University Archives.)