Seton Hospital was created through a partnership between the Sisters of Charity of Cincinnati and the Eclectic Medical College. As described in Harvey Wickes Felter's book History of the Eclectic Medical Institute, Cincinnati, Ohio, 1845-1902, Seton Hospital was "constructed at an expense of $90,000,...and is located at 640 West Eighth Street, near Cutter. The building, a large stone-front structure, is located on a lot fronting sixty-three feet on Eighth Street, and running two hundred feet through to Ninth Street, thus giving a double street frontage and excellent light and ventilation." The hospital operated in the West End neighborhood of Cincinnati until 1925, when it merged with Good Samaritan Hospital.
From the guide to the Seton Hospital Collection, 1899-1925, 1923-1925, (University of Cincinnati, Health Sciences Library, Henry R. Winkler Center for the History of the Health Professions)