Mütter Museum.

In 1849, Dr. Isaac Parrish suggested that the College of Physicians of Philadelphia start a museum of pathological anatomy to preserve valuable material that might otherwise be lost to science. The collection grew rapidly until 1852, when Dr. Parrish died and the collection entered a period of inactivity.

On May 20, 1856, Dr. Thomas Dent Mütter wrote to the College that he was retiring from teaching because of ill health and wished to offer the guardianship of his personal museum to the College of Physicians as the "body best qualified by the character of its members and the nature of its pursuits for undertaking the trust." A popular professor of surgery at Jefferson Medical College, Mütter had amassed a unique and valuable collection of anatomical and pathological materials for use in his classes. Accompanying the collection would be an endowment of $30,000, the income from which was to pay for the salaries of a curator, a lecturer, and for the care and enlargement of the museum. At the time, the College was holding its meetings in rented quarters; Mütter specified that the College must erect a suitable fire-proof building within five years of signing the agreement.

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