Macewen, Sir William (1848-1924: surgeon, Regius Professor of Surgery, University of Glasgow, Scotland, 1892-1924)

Sir William Macewen was born at Rothesay, Isle of Bute, Scotland, on the 22 June 1848 . He was educated at the Collegiate School at Glasgow, Scotland, and went on to study at the University of Glasgow . He graduated from the University as MB CM in 1869, and as MD in 1872 . In 1870, he became superintendent of Belvidere Hospital, Glasgow , Glasgow, and in 1877 became a surgeon at Glasgow Royal Infirmary . He married Mary Watson in 1873 and they went on to have 3 sons and 3 daughters.

His career was noteworthy for his pioneering work on brain and bone surgery. In 1878 , he became the first person to remove a tumour from the brain; in 1879 he operated for the relief of subdural haemorrhage. He looked upon bones as living tissue and introduced a method of implanting small grafts to replace missing parts of limb-bones. In 1880 , he sewed such grafts into the arm of a boy to replace the shaft of the humerus which had been destroyed by disease. The operation was successful, and the patient regained a useful arm. In 1877 , he introduced a new method of rectifying knock-knee by cutting through the thigh-bone just above the knee by a subcutaneous operation. Macewen became interested in the biology of bone and carried out a long and critical series of experiments on animals in order to determine the manner in which bones grow and the conditions underlying their repair. He came to the conclusion that the membrane which covers bone (periosteum) cannot produce bone. He published an account of his inquiries in The Growth of Bone (1912), reserving his observations on the natural history of bone for The Growth and Shedding of the Antler of the Deer which appeared in 1921.

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