Shear, Murray J.

Biographical sketch: Murray J. Shear (1899-1983) spent the bulk of his career researching substances and methods which might prove effective in the eradication of cancer. He was a member of the National Cancer Institute's inaugural staff and he actively participated in international cancer organizations. While attending the City College of New York for his Bachelor's degree, he became interested in physical chemistry and research. He saw a philosophic basis for scientific research in the sense that research provided information upon which a philosophy could be constructed. Indeed, he felt that any philosophy was possible only upon an examination of information and knowledge. His work with cancer began when he joined the U.S. Public Health Service's cancer research division, located at Harvard, in 1931. This group of scientists formed the nucleus of what would become the National Cancer Institute (NCI) in 1939. He began investigating calcium's effect on cancer tumors and progressed to studying the ameliorative effects of bacterial toxins on cancerous tumors. During the 1940s and 1950s his experiments with a purified filtrate of bacillus prodigiosus, or Serratia marcescens (polysaccharide) excited much scientific interest. His chemical approach to the study of cancer eradication marked him as an early leader in the field of chemotherapy. During his career he also served as president of the American Association of Cancer Research, secretary general of the International Union Against Cancer (IUAC), and chairman of the IUAC's Chemotherapy Committee.

From the description of Murray J. Shear papers, 1908-1983. (National Library of Medicine). WorldCat record id: 62885182

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