Knobil, Ernst.

Dr. Ernst Knobil was a leader and pioneer in many areas of endocrinology, including growth and reproduction. Kr. Knobil's classic contributions include the species-specific effects of Growth Hormone (GH), a model for positive and negative estrogen feedback control of the menstrual cycle, and elucidation of the hypothalamic Gonadotrpin-Releasing Hormone (GnRH) pulse generator. His discovery that pulsatile GnRH stimulates Luteinizing Hormone (LH) secretion, altered the field of reproductive endocrinology. This observation also unmasked a pivotal role for pulsatile secretion as a mechanism of hormonal control.

The son of an Austrian parents, Dr. Knobil was born in Berlin, Germany on September 20, 1926. The Knobil family moved to Paris in the early 1930's. When the Germans invaded Paris in 1940, the family emigrated to New York City where he attended high school.

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